The research will involve ring design and testing, preclinical safety and efficacy evaluations, clinical evaluation, and end user testing including preferences for the physical properties of the ring. The Council is developing a user-controlled, multi-purpose prevention, non-hormonal intravaginal ring that will provide contraception and protection against sexually-transmitted infections with the added benefit of promoting vaginal health by helping to maintain optimal vaginal pH. We will be integrating end user feedback into our development program and incorporate favorable product attributes into our ring design, with the goal of increasing user acceptability and adherence. Current contraceptive multi-purpose prevention technologies under development contain hormones, which some women do not prefer. With male condoms, a perfect use offers about a 98 rate of effectiveness, with female condoms providing around 95. Male and female condoms are viable forms of birth control, and each comes with a specific percentage of success. Hormone-Free Hormone-Free Phexxi is a non-hormonal birth control gel. Together these common STIs and BV put women at higher risk for HIV, adverse birth outcomes and stillbirth and neonatal death. This one is a no-brainer, but sometimes a piece of advice needs to be repeated before it can really sink in. Phexxi ® Is the First and Only Hormone-Free Prescription Birth Control Gel That You Control Only When You Need It No daily regimens, no invasive procedures, just a quick pre-sex application. We are presenting to you a few options which the sexually active youth can use. For women who do not want any side effects of hormonal birth control methods, these non-hormonal birth control methods give them an option to still have control over their birthing plans. Globally, the overall incidence of bacterial vaginosis is 29.2% but up to 50% in sub-Saharan Africa and is associated with pre-term birth, endometriosis, urinary tract infections and pelvic inflammatory disease. Along with hormonal birth control methods, there are also non-hormonal methods.

WHO has estimated annual new infections of 127 million for chlamydia, 87 million for gonorrhea, and 500 million for HSV. There is an undeniable need for new technologies to address the overlapping global burdens of unintended pregnancy and sexually transmitted infections (STI’s) such as chlamydia, gonorrhea, HIV, herpes simplex virus and bacterial vaginosis. According to WHO, 214 million women per year want to avoid pregnancy but are not using a modern contraceptive method. The Population Council is advancing the development of a non-hormonal vaginal ring with potential to provide contraception along with broad microbial action against bacterial vaginosis-associated bacteria, HIV, HSV, chlamydia, and gonorrhea.

Non hormonal birth control